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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TERF1 All Species: 4.24
Human Site: T344 Identified Species: 10.37
UniProt: P54274 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54274 NP_003209.2 439 50246 T344 K K E R R V G T P Q S T K K K
Chimpanzee Pan troglodytes XP_001164723 439 50325 T344 K K E R R V G T L Q S T K K K
Rhesus Macaque Macaca mulatta XP_001083645 438 50257 G342 N K K E R R I G T L Q S T K K
Dog Lupus familis XP_546856 470 51528 P367 N Q V S M P S P A L K N K R P
Cat Felis silvestris
Mouse Mus musculus P70371 421 48205 L331 N E A R T G T L Q C E T T M E
Rat Rattus norvegicus NP_001012482 421 47744 L331 N E A R T G T L Q C E I A T K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516615 412 47652 R306 P A R Q D P P R L Q D R E P R
Chicken Gallus gallus NP_989711 354 40991 R267 L T G D I S S R V R P P S K K
Frog Xenopus laevis NP_001084426 420 49257 E288 N R D I N Q N E L T N T T N I
Zebra Danio Brachydanio rerio XP_695329 367 42492 K279 W K P E T A K K A H A T L K R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 96.5 21.9 N.A. 64.2 65.3 N.A. 20.9 38.7 40.3 29.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.8 97.7 40.4 N.A. 75.6 75.6 N.A. 40 53.5 58.7 48.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 26.6 6.6 N.A. 13.3 13.3 N.A. 6.6 13.3 6.6 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 40 20 N.A. 26.6 20 N.A. 26.6 20 26.6 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 20 0 0 10 0 0 20 0 10 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 20 0 0 0 0 0 % C
% Asp: 0 0 10 10 10 0 0 0 0 0 10 0 0 0 0 % D
% Glu: 0 20 20 20 0 0 0 10 0 0 20 0 10 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 20 20 10 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 0 0 10 10 0 10 0 0 0 0 10 0 0 10 % I
% Lys: 20 40 10 0 0 0 10 10 0 0 10 0 30 50 50 % K
% Leu: 10 0 0 0 0 0 0 20 30 20 0 0 10 0 0 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 50 0 0 0 10 0 10 0 0 0 10 10 0 10 0 % N
% Pro: 10 0 10 0 0 20 10 10 10 0 10 10 0 10 10 % P
% Gln: 0 10 0 10 0 10 0 0 20 30 10 0 0 0 0 % Q
% Arg: 0 10 10 40 30 10 0 20 0 10 0 10 0 10 20 % R
% Ser: 0 0 0 10 0 10 20 0 0 0 20 10 10 0 0 % S
% Thr: 0 10 0 0 30 0 20 20 10 10 0 50 30 10 0 % T
% Val: 0 0 10 0 0 20 0 0 10 0 0 0 0 0 0 % V
% Trp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _